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Hypoxic Cell Waves Around Necrotic Cores in Glioblastoma: A Biomathematical Model and Its Therapeutic Implications

Glioblastoma is a rapidly evolving high-grade astrocytoma that is distinguished pathologically from lower grade gliomas by the presence of necrosis and microvascular hyperplasia. Necrotic areas are typically surrounded by hypercellular regions known as “pseudopalisades” originated by local tumor ves...

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Detalles Bibliográficos
Autores principales: Martínez-González, Alicia, Calvo, Gabriel F., Pérez Romasanta, Luis A., Pérez-García, Víctor M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510407/
https://www.ncbi.nlm.nih.gov/pubmed/23151957
http://dx.doi.org/10.1007/s11538-012-9786-1