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Influence of the Length of the Alanine Spacer on the Acidic–Basic Properties of the Ac–Lys–(Ala)(n)–Lys–NH(2) Peptides (n = 0, 1, 2, …, 5)
By using the potentiometric titration method, we have determined the pK (a) values of the two terminal lysine groups in six alanine-based peptides differing in the length of the alanine chain: Ac–Lys–Lys–NH(2) (KK), Ac–Lys–Ala–Lys–NH(2) (KAK), Ac–Lys–Ala–Ala–Lys–NH(2) (KAK2), Ac–Lys–Ala–Ala–Ala–Lys–...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer US
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510421/ https://www.ncbi.nlm.nih.gov/pubmed/23204596 http://dx.doi.org/10.1007/s10953-012-9903-7 |