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RecA filament sliding on DNA facilitates homology search

During homologous recombination, RecA forms a helical filament on a single stranded (ss) DNA that searches for a homologous double stranded (ds) DNA and catalyzes the exchange of complementary base pairs to form a new heteroduplex. Using single molecule fluorescence imaging tools with high spatiotem...

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Detalles Bibliográficos
Autores principales: Ragunathan, Kaushik, Liu, Cheng, Ha, Taekjip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510455/
https://www.ncbi.nlm.nih.gov/pubmed/23240082
http://dx.doi.org/10.7554/eLife.00067