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Getting in (and out of) the loop: regulating higher order telomere structures

The DNA at the ends of linear chromosomes (the telomere) folds back onto itself and forms an intramolecular lariat-like structure. Although the telomere loop has been implicated in the protection of chromosome ends from nuclease-mediated resection and unscheduled DNA repair activities, it potentiall...

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Detalles Bibliográficos
Autores principales: Luke-Glaser, Sarah, Poschke, Heiko, Luke, Brian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510458/
https://www.ncbi.nlm.nih.gov/pubmed/23226680
http://dx.doi.org/10.3389/fonc.2012.00180