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Environmental toxins trigger PD-like progression via increased alpha-synuclein release from enteric neurons in mice

Pathological studies on Parkinson's disease (PD) patients suggest that PD pathology progresses from the enteric nervous system (ENS) and the olfactory bulb into the central nervous system. We have previously shown that environmental toxins acting locally on the ENS mimic this PD-like pathology...

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Detalles Bibliográficos
Autores principales: Pan-Montojo, Francisco, Schwarz, Mathias, Winkler, Clemens, Arnhold, Mike, O'Sullivan, Gregory A., Pal, Arun, Said, Jonas, Marsico, Giovanni, Verbavatz, Jean-Marc, Rodrigo-Angulo, Margarita, Gille, Gabriele, Funk, Richard H. W., Reichmann, Heinz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510466/
https://www.ncbi.nlm.nih.gov/pubmed/23205266
http://dx.doi.org/10.1038/srep00898