Distinct gating mechanisms revealed by the structures of a multi-ligand gated K(+) channel

The gating ring-forming RCK domain regulates channel gating in response to various cellular chemical stimuli in eukaryotic Slo channel families and the majority of ligand-gated prokaryotic K(+) channels and transporters. Here we present structural and functional studies of a dual RCK-containing, mul...

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Detalles Bibliográficos
Autores principales: Kong, Chunguang, Zeng, Weizhong, Ye, Sheng, Chen, Liping, Sauer, David Bryant, Lam, Yeeling, Derebe, Mehabaw Getahun, Jiang, Youxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2012
Materias:
Biophysics and Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510474/
https://www.ncbi.nlm.nih.gov/pubmed/23240087
http://dx.doi.org/10.7554/eLife.00184

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510474/
https://www.ncbi.nlm.nih.gov/pubmed/23240087
http://dx.doi.org/10.7554/eLife.00184

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