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Distinct gating mechanisms revealed by the structures of a multi-ligand gated K(+) channel
The gating ring-forming RCK domain regulates channel gating in response to various cellular chemical stimuli in eukaryotic Slo channel families and the majority of ligand-gated prokaryotic K(+) channels and transporters. Here we present structural and functional studies of a dual RCK-containing, mul...
Autores principales: | Kong, Chunguang, Zeng, Weizhong, Ye, Sheng, Chen, Liping, Sauer, David Bryant, Lam, Yeeling, Derebe, Mehabaw Getahun, Jiang, Youxing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510474/ https://www.ncbi.nlm.nih.gov/pubmed/23240087 http://dx.doi.org/10.7554/eLife.00184 |
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