Structure of Actin-related protein 8 and its contribution to nucleosome binding

Nuclear actin-related proteins (Arps) are subunits of several chromatin remodelers, but their molecular functions within these complexes are unclear. We report the crystal structure of the INO80 complex subunit Arp8 in its ATP-bound form. Human Arp8 has several insertions in the conserved actin fold...

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Detalles Bibliográficos
Autores principales: Gerhold, Christian B., Winkler, Duane D., Lakomek, Kristina, Seifert, Florian U., Fenn, Sebastian, Kessler, Brigitte, Witte, Gregor, Luger, Karolin, Hopfner, Karl-Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510490/
https://www.ncbi.nlm.nih.gov/pubmed/22977180
http://dx.doi.org/10.1093/nar/gks842

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510490/
https://www.ncbi.nlm.nih.gov/pubmed/22977180
http://dx.doi.org/10.1093/nar/gks842

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