Conformational transitions regulate the exposure of a DNA-binding domain in the RuvBL1–RuvBL2 complex

RuvBL1 and RuvBL2, also known as Pontin and Reptin, are AAA+ proteins essential in small nucleolar ribonucloprotein biogenesis, chromatin remodelling, nonsense-mediated messenger RNA decay and telomerase assembly, among other functions. They are homologous to prokaryotic RuvB, forming single- and do...

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Detalles Bibliográficos
Autores principales: López-Perrote, Andrés, Muñoz-Hernández, Hugo, Gil, David, Llorca, Oscar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510503/
https://www.ncbi.nlm.nih.gov/pubmed/23002137
http://dx.doi.org/10.1093/nar/gks871

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510503/
https://www.ncbi.nlm.nih.gov/pubmed/23002137
http://dx.doi.org/10.1093/nar/gks871

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