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Conformational transitions regulate the exposure of a DNA-binding domain in the RuvBL1–RuvBL2 complex
RuvBL1 and RuvBL2, also known as Pontin and Reptin, are AAA+ proteins essential in small nucleolar ribonucloprotein biogenesis, chromatin remodelling, nonsense-mediated messenger RNA decay and telomerase assembly, among other functions. They are homologous to prokaryotic RuvB, forming single- and do...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510503/ https://www.ncbi.nlm.nih.gov/pubmed/23002137 http://dx.doi.org/10.1093/nar/gks871 |