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Removal of a frameshift between the hsdM and hsdS genes of the EcoKI Type IA DNA restriction and modification system produces a new type of system and links the different families of Type I systems

The EcoKI DNA methyltransferase is a trimeric protein comprised of two modification subunits (M) and one sequence specificity subunit (S). This enzyme forms the core of the EcoKI restriction/modification (RM) enzyme. The 3′ end of the gene encoding the M subunit overlaps by 1 nt the start of the gen...

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Detalles Bibliográficos
Autores principales: Roberts, Gareth A., Chen, Kai, Cooper, Laurie P., White, John H., Blakely, Garry W., Dryden, David T. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510504/
https://www.ncbi.nlm.nih.gov/pubmed/23002145
http://dx.doi.org/10.1093/nar/gks876