The GyrA-box determines the geometry of DNA bound to gyrase and couples DNA binding to the nucleotide cycle

DNA gyrase catalyses the adenosine triphosphate-dependent introduction of negative supercoils into DNA. The enzyme binds a DNA-segment at the so-called DNA-gate and cleaves both DNA strands. DNA extending from the DNA-gate is bound at the perimeter of the cylindrical C-terminal domains (CTDs) of the...

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Detalles Bibliográficos
Autores principales: Lanz, Martin A., Klostermeier, Dagmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510516/
https://www.ncbi.nlm.nih.gov/pubmed/22977179
http://dx.doi.org/10.1093/nar/gks852

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510516/
https://www.ncbi.nlm.nih.gov/pubmed/22977179
http://dx.doi.org/10.1093/nar/gks852

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