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The GyrA-box determines the geometry of DNA bound to gyrase and couples DNA binding to the nucleotide cycle
DNA gyrase catalyses the adenosine triphosphate-dependent introduction of negative supercoils into DNA. The enzyme binds a DNA-segment at the so-called DNA-gate and cleaves both DNA strands. DNA extending from the DNA-gate is bound at the perimeter of the cylindrical C-terminal domains (CTDs) of the...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510516/ https://www.ncbi.nlm.nih.gov/pubmed/22977179 http://dx.doi.org/10.1093/nar/gks852 |