Genome-wide meta-analysis points to CTC1 and ZNF676 as genes regulating telomere homeostasis in humans

Leukocyte telomere length (LTL) is associated with a number of common age-related diseases and is a heritable trait. Previous genome-wide association studies (GWASs) identified two loci on chromosomes 3q26.2 (TERC) and 10q24.33 (OBFC1) that are associated with the inter-individual LTL variation. We...

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Detalles Bibliográficos
Autores principales: Mangino, Massimo, Hwang, Shih-Jen, Spector, Timothy D., Hunt, Steven C., Kimura, Masayuki, Fitzpatrick, Annette L., Christiansen, Lene, Petersen, Inge, Elbers, Clara C., Harris, Tamara, Chen, Wei, Srinivasan, Sathanur R., Kark, Jeremy D., Benetos, Athanase, El Shamieh, Said, Visvikis-Siest, Sophie, Christensen, Kaare, Berenson, Gerald S., Valdes, Ana M., Viñuela, Ana, Garcia, Melissa, Arnett, Donna K., Broeckel, Ulrich, Province, Michael A., Pankow, James S., Kammerer, Candace, Liu, Yongmei, Nalls, Michael, Tishkoff, Sarah, Thomas, Fridtjof, Ziv, Elad, Psaty, Bruce M., Bis, Joshua C., Rotter, Jerome I., Taylor, Kent D., Smith, Erin, Schork, Nicholas J., Levy, Daniel, Aviv, Abraham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Association Studies Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510758/
https://www.ncbi.nlm.nih.gov/pubmed/23001564
http://dx.doi.org/10.1093/hmg/dds382

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510758/
https://www.ncbi.nlm.nih.gov/pubmed/23001564
http://dx.doi.org/10.1093/hmg/dds382

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