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Oncogene Ras/Phosphatidylinositol 3-Kinase Signaling Targets Histone H3 Acetylation at Lysine 56

It is well established that the small GTPase Ras promotes tumor initiation by activating at least three different mediators: Raf, PI3K, and Ras-like (Ral) guanine nucleotide exchange factors. However, the exact mechanisms that underlie these different Ras signaling pathways, which are involved in tu...

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Detalles Bibliográficos
Autores principales: Liu, Yan, Wang, Da-Liang, Chen, Su, Zhao, Lei, Sun, Fang-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510844/
https://www.ncbi.nlm.nih.gov/pubmed/22982396
http://dx.doi.org/10.1074/jbc.M112.367847