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α-Cleavage of cellular prion protein

The cellular prion protein (PrP(C)) is subjected to various processing under physiological and pathological conditions, of which the α-cleavage within the central hydrophobic domain not only disrupts a region critical for both PrP toxicity and PrP(C) to PrP(Sc) conversion but also produces the N1 fr...

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Detalles Bibliográficos
Autores principales:	Liang, Jingjing, Kong, Qingzhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Landes Bioscience 2012
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510859/ https://www.ncbi.nlm.nih.gov/pubmed/23052041 http://dx.doi.org/10.4161/pri.22511

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