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Intronic SNPs of TP53 gene in chronic myeloid leukemia: Impact on drug response

BACKGROUND: TP53, located on chromosome 17p13, is one of the most mutated genes affecting many types of human cancers. Thus, we aimed at investigating the association of SNPs in TP53 gene with chronic myeloid leukemia (CML). MATERIALS AND METHODS: A total of 236 CML and 157 control samples were anal...

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Detalles Bibliográficos
Autores principales: Sailaja, K., Rao, V. R., Yadav, Satish, Reddy, R. Rajasekhar, Surekha, D., Rao, D. Nageswara, Raghunadharao, D., Vishnupriya, S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510914/
https://www.ncbi.nlm.nih.gov/pubmed/23225982
http://dx.doi.org/10.4103/0976-9668.101910