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Engineering of indole-based tethered biheterocyclic alkaloid meridianin into β-carboline-derived tetracyclic polyheterocycles via amino functionalization/6-endo cationic π-cyclization

A mild, efficient and versatile method has been developed for the construction of a functionalized natural product, meridianin, and its post conversion to pyrimido-β-carboline by cationic π- cyclization. The strategy involves the introduction of an amino group at the C-5 of the pyrimidine ring and u...

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Detalles Bibliográficos
Autores principales: Agarwal, Piyush Kumar, Dathi, Meena Devi, Saifuddin, Mohammad, Kundu, Bijoy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511029/
https://www.ncbi.nlm.nih.gov/pubmed/23209529
http://dx.doi.org/10.3762/bjoc.8.220