Cargando…
The multicomponent approach to N-methyl peptides: total synthesis of antibacterial (–)-viridic acid and analogues
Two syntheses of natural viridic acid, an unusual triply N-methylated peptide with two anthranilate units, are presented. The first one is based on peptide-coupling strategies and affords the optically active natural product in 20% overall yield over six steps. A more economical approach with only f...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Beilstein-Institut
2012
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511043/ https://www.ncbi.nlm.nih.gov/pubmed/23209543 http://dx.doi.org/10.3762/bjoc.8.234 |