An investigation of the auto-induction of and gender-related variability in the pharmacokinetics of dihydroartemisinin in the rat

BACKGROUND: Artemisinin (QHS) and its derivatives dihydroartemisinin (DHA), artemether and artesunate have become the first-line anti-malarials in areas of multidrug resistance. Declining plasma concentrations during the repeated dosing have been reported for QHS, artemether and less convincingly fo...

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Detalles Bibliográficos
Autores principales: Zhu, Fanping, Du, Fuying, Li, Xinxiu, Xing, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511063/
https://www.ncbi.nlm.nih.gov/pubmed/23171067
http://dx.doi.org/10.1186/1475-2875-11-379

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511063/
https://www.ncbi.nlm.nih.gov/pubmed/23171067
http://dx.doi.org/10.1186/1475-2875-11-379

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