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Glucarpidase to combat toxic levels of methotrexate in patients
In January 2012, glucarpidase (Voraxaze(®)) received approval from the US Food and Drug Administration for intravenous treatment of toxic plasma methotrexate concentrations due to impaired renal clearance. Methotrexate, an antifolate agent, has been used for over 60 years in the treatment of various...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Dove Medical Press
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511185/ https://www.ncbi.nlm.nih.gov/pubmed/23209370 http://dx.doi.org/10.2147/TCRM.S30135 |