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Dysfunctional telomeres in primary cells from Fanconi anemia FANCD2 patients

BACKGROUND: Fanconi anemia (FA) is characterized by sensitivity to DNA cross-linking agents, mild cellular, and marked clinical radio sensitivity. In this study we investigated telomeric abnormalities of non-immortalized primary cells (lymphocytes and fibroblasts) derived from FA patients of the FA-...

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Detalles Bibliográficos
Autores principales: Joksic, Ivana, Vujic, Dragana, Guc-Scekic, Marija, Leskovac, Andreja, Petrovic, Sandra, Ojani, Maryam, Trujillo, Juan P, Surralles, Jordi, Zivkovic, Maja, Stankovic, Aleksandra, Slijepcevic, Predrag, Joksic, Gordana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511208/
https://www.ncbi.nlm.nih.gov/pubmed/22980747
http://dx.doi.org/10.1186/2041-9414-3-6