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Construction of a recombinant eukaryotic expression vector containing PHD3 gene and its expression in HepG2 cells
Prolyl hydroxylase domain 3 (PHD3) is a hypoxia inducible factor-α (HIFα) regulator; it degrades HIFα in the presence of oxygen. Recently, there have been an increasing number of studies about the role of PHD3 in proliferation and apoptosis of cancer cells. However, most of the evidence for the role...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511251/ https://www.ncbi.nlm.nih.gov/pubmed/22898032 http://dx.doi.org/10.1186/1756-9966-31-64 |