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Oncolytic adenovirus armed with IL-24 Inhibits the growth of breast cancer in vitro and in vivo
BACKGROUND: Interleukin-24 (IL-24) is a cytokine that belongs to the IL-10 family. It can selectively induce cancer cell apoptosis which has been utilized as a cancer gene therapy strategy. METHODS: A recombinant type five adenovirus containing IL-24 gene (designated CNHK600-IL24) was constructed, w...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511263/ https://www.ncbi.nlm.nih.gov/pubmed/22640485 http://dx.doi.org/10.1186/1756-9966-31-51 |