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Oncolytic adenovirus armed with IL-24 Inhibits the growth of breast cancer in vitro and in vivo

BACKGROUND: Interleukin-24 (IL-24) is a cytokine that belongs to the IL-10 family. It can selectively induce cancer cell apoptosis which has been utilized as a cancer gene therapy strategy. METHODS: A recombinant type five adenovirus containing IL-24 gene (designated CNHK600-IL24) was constructed, w...

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Detalles Bibliográficos
Autores principales:	Zhu, Wei, Wei, Lai, Zhang, Hongwei, Chen, Junxue, Qin, Xinyu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511263/ https://www.ncbi.nlm.nih.gov/pubmed/22640485 http://dx.doi.org/10.1186/1756-9966-31-51

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