Identification of PPARgamma Partial Agonists of Natural Origin (I): Development of a Virtual Screening Procedure and In Vitro Validation

BACKGROUND: Although there are successful examples of the discovery of new PPARγ agonists, it has recently been of great interest to identify new PPARγ partial agonists that do not present the adverse side effects caused by PPARγ full agonists. Consequently, the goal of this work was to design, appl...

Descripción completa

Detalles Bibliográficos
Autores principales: Guasch, Laura, Sala, Esther, Castell-Auví, Anna, Cedó, Lidia, Liedl, Klaus R., Wolber, Gerhard, Muehlbacher, Markus, Mulero, Miquel, Pinent, Montserrat, Ardévol, Anna, Valls, Cristina, Pujadas, Gerard, Garcia-Vallvé, Santiago
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511273/
https://www.ncbi.nlm.nih.gov/pubmed/23226391
http://dx.doi.org/10.1371/journal.pone.0050816

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511273/
https://www.ncbi.nlm.nih.gov/pubmed/23226391
http://dx.doi.org/10.1371/journal.pone.0050816

Ejemplares similares