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Induction of cross-protection against influenza A virus by DNA prime-intranasal protein boost strategy based on nucleoprotein
BACKGROUND: The highly conserved nucleoprotein (NP) is an internal protein of influenza virus and is capable of inducing cross-protective immunity against different influenza A viruses, making it a main target of universal influenza vaccine. In current study, we characterized the immune response ind...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511278/ https://www.ncbi.nlm.nih.gov/pubmed/23173785 http://dx.doi.org/10.1186/1743-422X-9-286 |