Thioredoxin Reductase Deficiency Potentiates Oxidative Stress, Mitochondrial Dysfunction and Cell Death in Dopaminergic Cells

Mitochondria are considered major generators of cellular reactive oxygen species (ROS) which are implicated in the pathogenesis of neurodegenerative diseases such as Parkinson’s disease (PD). We have recently shown that isolated mitochondria consume hydrogen peroxide (H(2)O(2)) in a substrate- and r...

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Detalles Bibliográficos
Autores principales: Lopert, Pamela, Day, Brian J., Patel, Manisha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511321/
https://www.ncbi.nlm.nih.gov/pubmed/23226354
http://dx.doi.org/10.1371/journal.pone.0050683

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511321/
https://www.ncbi.nlm.nih.gov/pubmed/23226354
http://dx.doi.org/10.1371/journal.pone.0050683

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