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Expression of Yeast NDI1 Rescues a Drosophila Complex I Assembly Defect
Defects in mitochondrial electron transport chain (ETC) function have been implicated in a number of neurodegenerative disorders, cancer, and aging. Mitochondrial complex I (NADH dehydrogenase) is the largest and most complicated enzyme of the ETC with 45 subunits originating from two separate genom...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511326/ https://www.ncbi.nlm.nih.gov/pubmed/23226344 http://dx.doi.org/10.1371/journal.pone.0050644 |