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Expression of Yeast NDI1 Rescues a Drosophila Complex I Assembly Defect

Defects in mitochondrial electron transport chain (ETC) function have been implicated in a number of neurodegenerative disorders, cancer, and aging. Mitochondrial complex I (NADH dehydrogenase) is the largest and most complicated enzyme of the ETC with 45 subunits originating from two separate genom...

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Detalles Bibliográficos
Autores principales:	Cho, Jaehyoung, Hur, Jae H., Graniel, Jacqueline, Benzer, Seymour, Walker, David W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511326/ https://www.ncbi.nlm.nih.gov/pubmed/23226344 http://dx.doi.org/10.1371/journal.pone.0050644

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