Requirement for Zebrafish Ataxin-7 in Differentiation of Photoreceptors and Cerebellar Neurons

The expansion of a polyglutamine (polyQ) tract in the N-terminal region of ataxin-7 (atxn7) is the causative event in spinocerebellar ataxia type 7 (SCA7), an autosomal dominant neurodegenerative disorder mainly characterized by progressive, selective loss of rod-cone photoreceptors and cerebellar P...

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Detalles Bibliográficos
Autores principales: Yanicostas, Constantin, Barbieri, Elisa, Hibi, Masahiko, Brice, Alexis, Stevanin, Giovanni, Soussi-Yanicostas, Nadia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511343/
https://www.ncbi.nlm.nih.gov/pubmed/23226359
http://dx.doi.org/10.1371/journal.pone.0050705

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511343/
https://www.ncbi.nlm.nih.gov/pubmed/23226359
http://dx.doi.org/10.1371/journal.pone.0050705

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