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Requirement for Zebrafish Ataxin-7 in Differentiation of Photoreceptors and Cerebellar Neurons
The expansion of a polyglutamine (polyQ) tract in the N-terminal region of ataxin-7 (atxn7) is the causative event in spinocerebellar ataxia type 7 (SCA7), an autosomal dominant neurodegenerative disorder mainly characterized by progressive, selective loss of rod-cone photoreceptors and cerebellar P...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511343/ https://www.ncbi.nlm.nih.gov/pubmed/23226359 http://dx.doi.org/10.1371/journal.pone.0050705 |