p250GAP Is a Novel Player in the Cdh1-APC/Smurf1 Pathway of Axon Growth Regulation

Axon growth is an essential process during brain development. The E3 ubiquitin ligase Cdh1-APC has emerged as a critical regulator of intrinsic axon growth control. Here, we identified the RhoGAP p250GAP as a novel interactor of the E3 ubiquitin ligase Cdh1-APC and found that p250GAP promotes axon g...

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Detalles Bibliográficos
Autores principales: Kannan, Madhuvanthi, Lee, Shih-Ju, Schwedhelm-Domeyer, Nicola, Nakazawa, Takanobu, Stegmüller, Judith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511349/
https://www.ncbi.nlm.nih.gov/pubmed/23226367
http://dx.doi.org/10.1371/journal.pone.0050735

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511349/
https://www.ncbi.nlm.nih.gov/pubmed/23226367
http://dx.doi.org/10.1371/journal.pone.0050735

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