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Effects of the Small Molecule HERG Activator NS1643 on Kv11.3 Channels
NS1643 is one of the small molecule HERG (Kv11.1) channel activators and has also been found to increase erg2 (Kv11.2) currents. We now investigated whether NS1643 is also able to act as an activator of Kv11.3 (erg3) channels expressed in CHO cells. Activation of rat Kv11.3 current occurred in a dos...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511382/ https://www.ncbi.nlm.nih.gov/pubmed/23226420 http://dx.doi.org/10.1371/journal.pone.0050886 |