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Nicotine Reward and Affective Nicotine Withdrawal Signs Are Attenuated in Calcium/Calmodulin-Dependent Protein Kinase IV Knockout Mice

The influx of Ca(2+) through calcium-permeable nicotinic acetylcholine receptors (nAChRs) leads to activation of various downstream processes that may be relevant to nicotine-mediated behaviors. The calcium activated protein, calcium/calmodulin-dependent protein kinase IV (CaMKIV) phosphorylates the...

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Detalles Bibliográficos
Autores principales: Jackson, Kia J., Sanjakdar, Sarah S., Chen, Xiangning, Damaj, M. Imad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511389/
https://www.ncbi.nlm.nih.gov/pubmed/23226481
http://dx.doi.org/10.1371/journal.pone.0051154