Identification and Characterisation of the RalA-ERp57 Interaction: Evidence for GDI Activity of ERp57

RalA is a membrane-associated small GTPase that regulates vesicle trafficking. Here we identify a specific interaction between RalA and ERp57, an oxidoreductase and signalling protein. ERp57 bound specifically to the GDP-bound form of RalA, but not the GTP-bound form, and inhibited the dissociation...

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Detalles Bibliográficos
Autores principales: Brymora, Adam, Duggin, Iain G., Berven, Leise A., van Dam, Ellen M., Roufogalis, Basil D., Robinson, Phillip J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511393/
https://www.ncbi.nlm.nih.gov/pubmed/23226417
http://dx.doi.org/10.1371/journal.pone.0050879

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511393/
https://www.ncbi.nlm.nih.gov/pubmed/23226417
http://dx.doi.org/10.1371/journal.pone.0050879

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