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Identification and Characterisation of the RalA-ERp57 Interaction: Evidence for GDI Activity of ERp57
RalA is a membrane-associated small GTPase that regulates vesicle trafficking. Here we identify a specific interaction between RalA and ERp57, an oxidoreductase and signalling protein. ERp57 bound specifically to the GDP-bound form of RalA, but not the GTP-bound form, and inhibited the dissociation...
Autores principales: | Brymora, Adam, Duggin, Iain G., Berven, Leise A., van Dam, Ellen M., Roufogalis, Basil D., Robinson, Phillip J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511393/ https://www.ncbi.nlm.nih.gov/pubmed/23226417 http://dx.doi.org/10.1371/journal.pone.0050879 |
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