Suppression of Rap1 Impairs Cardiac Myofibrils and Conduction System in Zebrafish

Numerous studies have revealed that Rap1 (Ras-proximate-1 or Ras-related protein 1), a small GTPase protein, plays a crucial role in mediating cAMP signaling in isolated cardiac tissues and cell lines. However, the involvement of Rap1 in the cardiac development in vivo is largely unknown. By injecti...

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Detalles Bibliográficos
Autores principales: Dong, Wei, Yang, Zhenglin, Yang, Fan, Wang, Jialiang, Zhuang, Yan, Xu, Chongren, Zhang, Bo, Tian, Xiao-Li, Liu, Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511394/
https://www.ncbi.nlm.nih.gov/pubmed/23226434
http://dx.doi.org/10.1371/journal.pone.0050960

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511394/
https://www.ncbi.nlm.nih.gov/pubmed/23226434
http://dx.doi.org/10.1371/journal.pone.0050960

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