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GDF5 Regulates TGFß-Dependent Angiogenesis in Breast Carcinoma MCF-7 Cells: In Vitro and In Vivo Control by Anti-TGFß Peptides

BACKGROUND: TGFß overproduction in cancer cells is one of the main characteristics of late tumor progression being implicated in metastasis, tumor growth, angiogenesis and immune response. We investigated the therapeutic efficacy of anti-TGFß peptides in the control of angiogenesis elicited by condi...

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Detalles Bibliográficos
Autores principales: Margheri, Francesca, Schiavone, Nicola, Papucci, Laura, Magnelli, Lucia, Serratì, Simona, Chillà, Anastasia, Laurenzana, Anna, Bianchini, Francesca, Calorini, Lido, Torre, Eugenio, Dotor, Javier, Feijoo, Esperanza, Fibbi, Gabriella, Del Rosso, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511424/
https://www.ncbi.nlm.nih.gov/pubmed/23226264
http://dx.doi.org/10.1371/journal.pone.0050342