Characterization of LEDGF/p75 Genetic Variants and Association with HIV-1 Disease Progression

BACKGROUND: As Lens epithelium-derived growth factor (LEDGF/p75) is an important co-factor involved in HIV-1 integration, the LEDGF/p75-IN interaction is a promising target for the new class of allosteric HIV integrase inhibitors (LEDGINs). Few data are available on the genetic variability of LEDGF/...

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Detalles Bibliográficos
Autores principales: Messiaen, Peter, De Spiegelaere, Ward, Alcami, Jose, Vervisch, Karen, Van Acker, Petra, Verhasselt, Bruno, Meuwissen, Pieter, Calonge, Esther, Gonzalez, Nuria, Gutierrez-Rodero, Felix, Rodriguez-Martín, Carmen, Sermijn, Erica, Poppe, Bruce, Vogelaers, Dirk, Verhofstede, Chris, Vandekerckhove, Linos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511443/
https://www.ncbi.nlm.nih.gov/pubmed/23226247
http://dx.doi.org/10.1371/journal.pone.0050204

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511443/
https://www.ncbi.nlm.nih.gov/pubmed/23226247
http://dx.doi.org/10.1371/journal.pone.0050204

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