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Systemic Perturbation of the ERK Signaling Pathway by the Proteasome Inhibitor, MG132
Inhibition of the ubiquitin-proteasome protein degradation pathway has been identified as a viable strategy for anti-tumor therapy based on its broad effects on cell proliferation. By the same token, the variety of elicited effects confounds the interpretation of cell-based experiments using proteas...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511445/ https://www.ncbi.nlm.nih.gov/pubmed/23226437 http://dx.doi.org/10.1371/journal.pone.0050975 |