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MAPK Signaling Drives Inflammation in LPS-Stimulated Cardiomyocytes: The Route of Crosstalk to G-Protein-Coupled Receptors

Profound cardiovascular dysfunction is an important cause of mortality from septic shock. The molecular underpinnings of cardiac dysfunction during the inflammatory surge of early sepsis are not fully understood. MAPKs are important signal transducers mediating inflammation whereas G-protein signali...

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Detalles Bibliográficos
Autores principales: Frazier, W. Joshua, Xue, Jianjing, Luce, Wendy A., Liu, Yusen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511453/
https://www.ncbi.nlm.nih.gov/pubmed/23226236
http://dx.doi.org/10.1371/journal.pone.0050071