Role of Histone Deacetylases in Gene Regulation at Nuclear Lamina

Theoretical models suggest that gene silencing at the nuclear periphery may involve “closing” of chromatin by transcriptional repressors, such as histone deacetylases (HDACs). Here we provide experimental evidence confirming these predictions. Histone acetylation, chromatin compactness, and gene rep...

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Detalles Bibliográficos
Autores principales: Milon, Beatrice C., Cheng, Haibo, Tselebrovsky, Mikhail V., Lavrov, Sergei A., Nenasheva, Valentina V., Mikhaleva, Elena A., Shevelyov, Yuri Y., Nurminsky, Dmitry I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511463/
https://www.ncbi.nlm.nih.gov/pubmed/23226217
http://dx.doi.org/10.1371/journal.pone.0049692

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511463/
https://www.ncbi.nlm.nih.gov/pubmed/23226217
http://dx.doi.org/10.1371/journal.pone.0049692

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