Onset of Immune Senescence Defined by Unbiased Pyrosequencing of Human Immunoglobulin mRNA Repertoires

The immune system protects us from foreign substances or pathogens by generating specific antibodies. The variety of immunoglobulin (Ig) paratopes for antigen recognition is a result of the V(D)J rearrangement mechanism, while a fast and efficient immune response is mediated by specific immunoglobul...

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Detalles Bibliográficos
Autores principales: Rubelt, Florian, Sievert, Volker, Knaust, Florian, Diener, Christian, Lim, Theam Soon, Skriner, Karl, Klipp, Edda, Reinhardt, Richard, Lehrach, Hans, Konthur, Zoltán
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511497/
https://www.ncbi.nlm.nih.gov/pubmed/23226220
http://dx.doi.org/10.1371/journal.pone.0049774

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511497/
https://www.ncbi.nlm.nih.gov/pubmed/23226220
http://dx.doi.org/10.1371/journal.pone.0049774

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