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MicroRNA 218 Mediates the Effects of Tbx5a Over-Expression on Zebrafish Heart Development
tbx5, a member of the T-box gene family, encodes one of the key transcription factors mediating vertebrate heart development. Tbx5 function in heart development appears to be exquisitely sensitive to gene dosage, since both haploinsufficiency and gene duplication generate the cardiac abnormalities a...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511548/ https://www.ncbi.nlm.nih.gov/pubmed/23226307 http://dx.doi.org/10.1371/journal.pone.0050536 |