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MicroRNA 218 Mediates the Effects of Tbx5a Over-Expression on Zebrafish Heart Development

tbx5, a member of the T-box gene family, encodes one of the key transcription factors mediating vertebrate heart development. Tbx5 function in heart development appears to be exquisitely sensitive to gene dosage, since both haploinsufficiency and gene duplication generate the cardiac abnormalities a...

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Detalles Bibliográficos
Autores principales:	Chiavacci, Elena, Dolfi, Luca, Verduci, Lorena, Meghini, Francesco, Gestri, Gaia, Evangelista, Alberto Mercatanti Monica, Wilson, Stephen W., Cremisi, Federico, Pitto, Letizia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511548/ https://www.ncbi.nlm.nih.gov/pubmed/23226307 http://dx.doi.org/10.1371/journal.pone.0050536

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