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Protective Effects of Acyl-coA Thioesterase 1 on Diabetic Heart via PPARα/PGC1α Signaling

BACKGROUND: Using fatty acids (FAs) exclusively for ATP generation was reported to contribute to the development of diabetic cardiomyopathy. We studied the role of substrate metabolism related genes in the heart of the diabetes to find out a novel therapeutic target for diabetic cardiomyopathy. METH...

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Detalles Bibliográficos
Autores principales: Yang, Shenglan, Chen, Chen, Wang, Hong, Rao, Xiaoquan, Wang, Feng, Duan, Quanlu, Chen, Fuqiong, Long, Guangwen, Gong, Wei, Zou, Ming-Hui, Wang, Dao Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511550/
https://www.ncbi.nlm.nih.gov/pubmed/23226270
http://dx.doi.org/10.1371/journal.pone.0050376