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Caspase-1 and IL-1β Processing in a Teleost Fish

Interleukine-1β (IL-1β) is the most studied pro-inflammatory cytokine, playing a central role in the generation of systemic and local responses to infection, injury, and immunological challenges. In mammals, IL-1β is synthesized as an inactive 31 kDa precursor that is cleaved by caspase-1 generating...

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Detalles Bibliográficos
Autores principales: Reis, Marta I. R., do Vale, Ana, Pereira, Pedro J. B., Azevedo, Jorge E., dos Santos, Nuno M. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511578/
https://www.ncbi.nlm.nih.gov/pubmed/23226286
http://dx.doi.org/10.1371/journal.pone.0050450