Vitamin D receptor agonists increase klotho and osteopontin while decreasing aortic calcification in mice with chronic kidney disease fed a high phosphate diet

Vascular calcification is common in chronic kidney disease, where cardiovascular mortality remains the leading cause of death. Patients with kidney disease are often prescribed vitamin D receptor agonists (VDRAs) that confer a survival benefit, but the underlying mechanisms remain unclear. Here we t...

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Detalles Bibliográficos
Autores principales: Lau, Wei Ling, Leaf, Elizabeth M., Hu, Ming Chang, Takeno, Marc M., Kuro-o, Makoto, Moe, Orson W., Giachelli, Cecilia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511664/
https://www.ncbi.nlm.nih.gov/pubmed/22932118
http://dx.doi.org/10.1038/ki.2012.322

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511664/
https://www.ncbi.nlm.nih.gov/pubmed/22932118
http://dx.doi.org/10.1038/ki.2012.322

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