Random Insertion of mCherry Into VP3 Domain of Adeno-associated Virus Yields Fluorescent Capsids With no Loss of Infectivity

Adeno-associated virus (AAV)-derived vectors are promising gene delivery systems, and a number of design strategies have been pursued to improve their performance. For example, genetic insertion of proteins into the capsid may be used to achieve vector retargeting, reduced immunogenicity, or to trac...

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Detalles Bibliográficos
Autores principales: Judd, Justin, Wei, Fang, Nguyen, Peter Q, Tartaglia, Lawrence J, Agbandje-McKenna, Mavis, Silberg, Jonathan J, Suh, Junghae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Methods - Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511673/
https://www.ncbi.nlm.nih.gov/pubmed/23629029
http://dx.doi.org/10.1038/mtna.2012.46

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511673/
https://www.ncbi.nlm.nih.gov/pubmed/23629029
http://dx.doi.org/10.1038/mtna.2012.46

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